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Cohort Acronym

Cohort type
General population-based cohort

Dementia (unclassified), Mild cognitive impairment (MCI), Parkinson's disease, Subjective memory complaints (SMC) or subjective cognitive decline (SCD)

Participant type
No diagnosis

Recruitment Period 2008 
Sample size at start or planned sample size if still recruiting 7524  
Estimated Current Sample Size 5,000 to 9,999 
Age at Recruitment >65   
Gender Male and Female 

CFAS II based in England and Wales started in 2008, and builds on the design and infrastructure of original CFAS. It has provided data on generational and geographical differences including people in institutions. It will also provide important base-line information on older people aged 65-84 in 2007-2008 who will reach the age of greatest frailty during the 2020s when the peak in the number of people aged 85 or over is expected and at a time when major therapeutic interventions for dementia could be expected to have an effect. Participants were followed up by interview throughout 2010-2011.

CFAS II is part of the Dementias Platform UK (DPUK), a multi-million pound public-private partnership to accelerate progress in dementias research http://www.mrc.ac.uk/research/facilities/dementias-platform-uk/

Last update: 13/01/2017

Country United Kingdom 
Contact details
Institution name University of Cambridge, School of Clinical Medicine 
Principal Investiator (PI) Professor Carol Brayne 
Contact email [email protected] 
Contact phone number +44 (0) 1223 330312 
Address CFAS
Institute of Public Health
Forvie Site
University of Cambridge School of Clinical Medicine
Cambridge Biomedical Campus
CB2 0SR 
Funders (Core support) Alzheimer's Society 

Variables Collected

Brain related measures: Behaviour, Cognitive function, Mental health, Neurological
Funtional rating: Individual physiological, Individual psychological
Anthropometric: N/A
Physical: Cardiovascular, Hearing and Vision, Respiratory
Biological samples: Other, Saliva
Genotyping: N/A
Brain imaging: N/A
Brain banking: Consent for brain donation
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: Education, Ethnic group, Family circumstances, Housing and accommodation, Marital status, Occupation and employment, Unpaid care
Health service utilisation: Formal health and social care service utilisation including private care
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