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Cohort Acronym

Cohort type
General population-based cohort

Parkinson's disease

Participant type
No diagnosis

Recruitment Period 1998-2005 
Sample size at start or planned sample size if still recruiting 2262  
Estimated Current Sample Size 0 to 4,999 
Age at Recruitment 92-100   
Gender Male and Female 

The overall goal was to establish a genetic-epidemiological database to shed light on the aging process among the extremely old, focusing on physical and cognitive functioning. In the first wave 2,262 Danes born in 1905 participated in a home-based 2-hour multidimensional interview, including cognitive and physical performance tests and collection of DNA, carried out by lay interviewers. Population-based registers were used to evaluate representativeness.

The first wave took place in 1998 and participants were followed-up in 2000 and 2003. In 2005 all the surviving birth cohort members were invited to participate irrespective of previous participation:

  • Wave 1: 2262 participants (1653 with biological sample)
  • Wave 2: 1086 participants
  • Wave 3: 437 participants
  • Wave 4: 256 participants

Last update – 30/01/2017

Country Denmark 
Contact details
Institution name University of Southern Denmark 
Principal Investiator (PI) Professor Kaare Christensen and Professor Bernard Jeune 
Contact email PI Email: [email protected] PI Email: [email protected] 
Contact phone number +45 65503049 
Address University of Southern Denmark
Epidemiology, Biostatistics and Biodemography,
Funders (Core support) Danish National Research Foundation
United States Department of Health and Human Services
National Institutes of Health
National Institute on Aging (NIA) 

Variables Collected

Brain related measures: Cognitive function, Mental health, Neurological
Funtional rating: Individual physiological, Individual psychological
Anthropometric: Height, Waist circumference, Weight
Physical: Cardiovascular, Hearing and Vision, Musculoskeletal, Reproductive, Respiratory
Biological samples: Blood, Other
Genotyping: Gene screening
Brain imaging: N/A
Brain banking: N/A
Lifestyle: Alcohol, Physical activity, Smoking
Socio-economic: Education, Family circumstances, Housing and accommodation, Informal support, Marital status, Occupation and employment, Unpaid care
Health service utilisation: Formal health and social care service utilisation including private care
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