Cohort Acronym
ESPRIT
Cohort type
General population-based cohort
Disease
Alzheimer's disease, Dementia (unclassified), Mild cognitive impairment (MCI), Parkinson's disease, Subjective memory complaints (SMC) or subjective cognitive decline (SCD), Vascular dementia
Participant type
No diagnosis
Profile
ESPRIT
Cohort type
General population-based cohort
Disease
Alzheimer's disease, Dementia (unclassified), Mild cognitive impairment (MCI), Parkinson's disease, Subjective memory complaints (SMC) or subjective cognitive decline (SCD), Vascular dementia
Participant type
No diagnosis
Profile
Recruitment Period
1999-2001
Sample size at start or planned sample size if still recruiting
1863
Estimated Current Sample Size
0 to 4,999
Age at Recruitment
65 and over
Gender
Male and Female
Abstract
For the Esprit study, 1863 non-institutionalized persons aged 65 years and over were randomly recruited in 1999 from the Montpellier district electoral rolls, and re-examined 6-times at 2-3 yearly intervals. Objectives:
1) To determine current and lifetime prevalence as well as incidence of psychiatric disorder in the elderly;
2) to determine the risk factors for these disorders, their relative weight and interactions;
3) to study clinical heterogeneity;
4) to estimate the probability of transition towards a subsyndromic state or a given pathology;
5) to elaborate predictive etiological models.
Country
France
Contact details
Institution name
Novartis, Agence Nationale de la Recherche, Regional government of Languedoc Roussillon, Inserm
Principal Investiator (PI)
Marie-Laure Ancelin and Karen Ritchie
Contact email
PI email: [email protected]; PI email: [email protected]
Contact phone number
Tel: +33 4 99 61 45 62
Address
Inserm U1061, Montpellier, France
Funders (Core support)
Novartis, Agence Nationale de la Recherche, Regional government of Languedoc Roussillon, Inserm
Variables Collected
Brain related measures: N/A
Funtional rating: Individual psychological
Anthropometric: Blood pressure, Height, Hip circumference, Waist circumference, Weight
Physical: Cardiovascular, Hearing and Vision, Reproductive, Respiratory
Biological samples: Blood, Other, Saliva
Genotyping: Gene screening
Brain imaging: Magnetic resonance imaging (MRI), Magnetoencephalography (MEG)
Brain banking: N/A
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: Education, Ethnic group, Family circumstances, Housing and accommodation, Income and finances, Marital status, Occupation and employment
Health service utilisation: Formal health and social care service utilisation including private care