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Cohort Acronym

Cohort type
General population-based cohort

Alzheimer's disease, Dementia (unclassified), Mild cognitive impairment (MCI), Parkinson's disease, Subjective memory complaints (SMC) or subjective cognitive decline (SCD), Vascular dementia

Participant type
No diagnosis

Recruitment Period 1999-2001 
Sample size at start or planned sample size if still recruiting 1863  
Estimated Current Sample Size 0 to 4,999 
Age at Recruitment 65 and over   
Gender Male and Female 

For the Esprit study, 1863 non-institutionalized persons aged 65 years and over were randomly recruited in 1999 from the Montpellier district electoral rolls, and re-examined 6-times at 2-3 yearly intervals. Objectives:

1) To determine current and lifetime prevalence as well as incidence of psychiatric disorder in the elderly;
2) to determine the risk factors for these disorders, their relative weight and interactions;
3) to study clinical heterogeneity;
4) to estimate the probability of transition towards a subsyndromic state or a given pathology;
5) to elaborate predictive etiological models.

Country France 
Contact details
Institution name Novartis, Agence Nationale de la Recherche, Regional government of Languedoc Roussillon, Inserm 
Principal Investiator (PI) Marie-Laure Ancelin and Karen Ritchie 
Contact email PI email: [email protected]; PI email: [email protected] 
Contact phone number Tel: +33 4 99 61 45 62 
Address Inserm U1061, Montpellier, France 
Funders (Core support) Novartis, Agence Nationale de la Recherche, Regional government of Languedoc Roussillon, Inserm 

Variables Collected

Brain related measures: N/A
Funtional rating: Individual psychological
Anthropometric: Blood pressure, Height, Hip circumference, Waist circumference, Weight
Physical: Cardiovascular, Hearing and Vision, Reproductive, Respiratory
Biological samples: Blood, Other, Saliva
Genotyping: Gene screening
Brain imaging: Magnetic resonance imaging (MRI), Magnetoencephalography (MEG)
Brain banking: N/A
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: Education, Ethnic group, Family circumstances, Housing and accommodation, Income and finances, Marital status, Occupation and employment
Health service utilisation: Formal health and social care service utilisation including private care
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