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Cohort Acronym

Cohort type
General population-based cohort

Alzheimer's disease, Dementia (unclassified), Frontotemporal dementia, Lewy body disease, Mild cognitive impairment (MCI), Parkinson's disease, Subjective memory complaints (SMC) or subjective cognitive decline (SCD), Vascular dementia

Participant type
No diagnosis

Recruitment Period 2007-present 
Sample size at start or planned sample size if still recruiting 1002  
Estimated Current Sample Size  
Age at Recruitment >65   
Gender Male and Female 

The health of the agricultural population has been previously explored, particularly in relation to the farming exposures and among professionally active individuals. However, few studies specifically focused on health and aging among elders retired from agriculture. Yet, this population faces the long-term effects of occupational exposures and multiple difficulties related to living and aging in rural area (limited access to shops, services, and practitioners). However, these difficulties may be counter-balanced by advantages related to healthier lifestyle, richer social support and better living environment. The general aim of the AMI cohort was to study health and aging in elderly farmers living in rural area through a multidisciplinary approach, with a main focus on dementia.

The study started in 2007, with two follow-up visits over 5 years. Baseline visits were conducted at home by a neuropsychologist then by a geriatrician for all cases suspected of dementia, for all subjects suspected of being demented. The 10-year visit is currently on going.

Country France 
Contact details
Institution name Unité INSERM U1219 
Principal Investiator (PI) Dartigues Jean-Francois 
Contact email PI email: [email protected] 
Contact phone number Tel: +33 (0)5 57 57 15 96 
Address 146 rue Léo Saignat 33076 Bordeaux cedex 
Funders (Core support) The Association de Gestion pour le Compte des Institutions Complémentaires Agricoles, the Caisse Mutuelle Autonome de Retraites Complémentaires Agricoles, the Caisse de Retraite Complémentaire des Cadres de l’Agriculture, the Caisse Centrale de Prévoyance Mutuelle Agricole Prévoyance, the Caisse de Prévoyance des Cadres d’Entreprises Agricoles, Agri Prévoyance, the Mutualité Sociale Agricole de Gironde, the Caisse Centrale de la Mutualité Sociale Agricole, and the Caisse Nationale de Solidarité et d’Autonomie, Caisse Nationale de Solidarité pour l’Autonomie, SCOR. 

Variables Collected

Brain related measures: N/A
Funtional rating: Caregiver, Individual physiological, Individual psychological
Anthropometric: Blood pressure, Height, Hip circumference, Waist circumference, Weight
Physical: Cardiovascular, Hearing and Vision, Musculoskeletal, Respiratory
Biological samples: Blood
Genotyping: Gene screening
Brain imaging: Magnetic resonance imaging (MRI), Positron emission tomography (PET) - amyloid, Positron emission tomography (PET) fluorine18 flurodeoxyglucose (FDG)
Brain banking: N/A
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: Education, Family circumstances, Informal support, Martial status, Occupation and employment, Unpaid care
Health service utilisation: Formal health and social care service utilisation including private care
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