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Cohort Acronym

Cohort type
General population-based cohort

Alzheimer's disease, Parkinson's disease, Subjective memory complaints (SMC) or subjective cognitive decline (SCD)

Participant type
No diagnosis

Recruitment Period 2004,2009 and 2014 
Sample size at start or planned sample size if still recruiting 4731  
Estimated Current Sample Size 0 to 4,999 
Age at Recruitment 65-70   
Gender Male and Female 

The Lc65+ project is a longitudinal population-based study focusing on the development of frailty after the age of 65. The main methods in the Lc65+ study are:

ユ long term observation of subjects, beginning at 65 to 70 years, an age when frailty is still unusual, in order to study its initiation and development;
ユ prospective data collection on a large range of health dimensions, including psycho-social characteristics, in order to investigate the temporal sequence linking frailty, its risk factors, modulators, and outcomes:
ユ a population approach considering frailty as a central parameter of health in ageing populations that is useful not only for surveillance, but also for the evaluation of preventive interventions.

Follow-up is based on a yearly questionnaire sent by mail to the participant’s home. In addition, subjects are invited to the study center every three years for an interview and examination similar to those performed at baseline. The follow-up is unlimited in time and is not interrupted in the case of nursing home admission.

Last Update 21/09/2017

Country Switzerland 
Contact details
Institution name Lausanne University Institute of Social and Preventive Medicine (IUMSP) 
Principal Investiator (PI) Prof. Brigitte Santos-Eggimann 
Contact email Email: [email protected] PI Email: [email protected]  
Contact phone number Tel: +41 21 314 97 70 
Address Lausanne cohorte Lc65+
CHUV - Institute of Social and Preventive Medicine
Health Services Unit
Biopole 2, Route de la Corniche 10, SA-V
CH-1010 Lausanne 
Funders (Core support) City of Lausanne
Public Health Department of the Vaud canton, Lausanne
Lausanne University Hospital (CHUV)
Institute of Social and Preventive Medicine (IUMSP), CHUV, Lausanne
Community Medicine and Health Department (DUMSC), CHUV, Lausanne
Geriatrics and Geriatric Rehabilitation Service, CHUV, Lausanne
Ambulatory Medical Policlinic (PMU), Lausanne
Loterie Romande
Faculty of Biology and Medicine, University of Lausanne
Swiss National Foundation for Scientific Research (SNF) 

Variables Collected

Brain related measures: Cognitive function
Funtional rating: Individual psychological
Anthropometric: Blood pressure, Height, Hip circumference, Waist circumference, Weight
Physical: Hearing and Vision
Biological samples: N/A
Genotyping: N/A
Brain imaging: N/A
Brain banking: N/A
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: Family circumstances, Housing and accommodation, Income and finances, Informal support, Occupation and employment
Health service utilisation: Formal health and social care service utilisation including private care
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