Export as PDF
Cohort Acronym
LSCC
Cohort typeGeneral population-based cohort
Disease
Alzheimer's disease, Mild cognitive impairment (MCI)
Participant type
No diagnosis
Profile
Recruitment Period
1983
Sample size at start or planned sample size if still recruiting
6,342
Estimated Current Sample Size
Age at Recruitment
46-92
Gender
Male and Female
Abstract
The longitudinal Study of Cognitive Change in Normal Healthy Old Age (LSCC) is a population study including 6,342 healthy residence of Greater Manchester and Newcastle-upon-Tyne aged from 42 to 92 in 1983. Two different batteries of cognitive tests were alternately administered biennially with additional questionnaires and Dna sample collection until 2003. The aims of the study were to:
to determine sources of variations in rates of cognitive change between individuals
to identify factors that slow or accelerate cognitive ageing and that prolong mental productivity or accelerate decline
to generate and test functional models for the processes of biological ageing, especially of ageing of the brain and the central nervous system
to test whether the neurophysiological and consequent cognitive changes differ in idiosyncratic patterns between individuals
Country
United Kingdom
Contact details
Institution name
University of Manchester
Website
http://www.tandfonline.com/doi/abs/10.1080/13825580490511116
Principal Investiator (PI)
Patrick Rabbitt
Contact phone number
Address
University of Manchester
Age and Cognitive Performance Research Centre
Oxford Road
Manchester
M13 9PL
UK
Funders (Core support)
U.K. Social Science Research Council (1983 to 1988), Medical Research Council (MRC), Economic and Social Research Council (ESRC)
Variables Collected
Brain related measures: N/A
Funtional rating: Individual physiological, Individual psychological
Anthropometric: N/A
Physical: N/A
Biological samples: Blood, Saliva, Urine
Genotyping: N/A
Brain imaging: Magnetic resonance imaging (MRI)
Brain banking: N/A
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: Education, Ethnic group, Family circumstances, Housing and accommodation, Informal support, Marital status, Occupation and employment
Health service utilisation: N/A
Export as PDF
