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Cohort Acronym

Cohort type
General population-based cohort


Participant type
No diagnosis

Recruitment Period 2006 
Sample size at start or planned sample size if still recruiting 1042  
Estimated Current Sample Size 0 to 4,999 
Age at Recruitment >85   
Gender Male and Female 

In May 2006 a multidisciplinary team in the Institute for Ageing and Health at Newcastle University began a major groundbreaking study of the lives of those aged 85 years and older.
The study aimed to:

  • Assess, in great detail, the spectrum of health in the oldest old.
  • Examine the associations of health trajectories and outcomes with biological, clinical and social factors as the cohort ages.
  • Identify factors which contribute to the maintenance of health and independence.
  • Advance understanding of the biological nature of human ageing.

Eligible individuals will be all those who turn 85 during the year 2006 (i.e. born in 1921) and who are registered with a Newcastle or North Tyneside general practice. Participants will be visited in their current residence (own home or institution) by a research nurse at baseline, 18 months and 36 months. The assessment protocol entails a detailed multi-dimensional health assessment together with review of general practice medical records. Participants will be flagged with the NHS Central Register to provide details of the date and cause of death.

Last update: 17/01/2017

Country United Kingdom 
Contact details
Institution name Newcastle University 
Principal Investiator (PI) Dr Rachel Duncan 
Contact email [email protected] 
Contact phone number +44 (0) 191 2081117 
Address Professor Carol Jagger
Biogerontology Research Building,
Institute of Health and Society,
Newcastle University Institute for Ageing,
Newcastle University,
Campus for Ageing and Vitality,
Newcastle upon Tyne,
NE4 5PL. 
Funders (Core support) Medical Research Council (MRC)
Biotechnology Biological Sciences Research Council (BBSRC)
Dunhill Medical Trust
Newcastle University 

Variables Collected

Brain related measures: Cognitive function, Mental health
Funtional rating: Individual physiological
Anthropometric: Blood pressure, Height, Hip circumference, Waist circumference, Weight
Physical: Cardiovascular, Hearing and Vision, Musculoskeletal, Reproductive, Respiratory
Biological samples: Blood
Genotyping: N/A
Brain imaging: N/A
Brain banking: N/A
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: Family circumstances, Income and finances, Informal support, Occupation and employment
Health service utilisation: Formal health and social care service utilisation including private care
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