PREVENT
Cohort type
Neurodegenerative disease-specific cohort
Disease
Alzheimer's disease, Dementia (unclassified), Frontotemporal dementia, Subjective memory complaints (SMC) or subjective cognitive decline (SCD), Vascular dementia
Participant type
At-risk diagnosis
Profile
The PREVENT Research Programme has established a cohort of individuals to explore differences in the brain and cognitive function in healthy people in mid-life (aged 40-59). People are grouped into high, mid and low risk based on their family history and APOE status (a well-known risk gene for Alzheimer’s disease).
650 participants are assessed on biological indicators including markers in blood, saliva, urine and spinal fluid as well as direct imaging of the brain’s structure and function. Changes in all of these markers will be monitored at 2 years to work out if risks that predict these changes. One of the main aims of the study is to identify the earliest signs of changes in the brain whilst people are still in good health.
Last update – 13/12/2017
PREVENT Research Programme
West London Cognitive Disorders Treatment and Research Unit
Imperial College London
Lakeside Mental Health Unit
West Middlesex Hospital site
Twickenham Road
Isleworth
TW7 6FY
Fidelity and Alzheimer's Association