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Cohort Acronym

Cohort type
General population-based cohort

Alzheimer's disease, Frontotemporal dementia, Lewy body disease, Mild cognitive impairment (MCI), Other NDs not listed, Subjective memory complaints (SMC) or subjective cognitive decline (SCD), Vascular dementia

Participant type
No diagnosis

Recruitment Period 2009-2014 
Sample size at start or planned sample size if still recruiting 1321  
Estimated Current Sample Size 0 to 4,999 
Age at Recruitment 70-74   
Gender Male and Female 

InveCe.Ab (Invecchiamento Cerebrale ad Abbiategrasso) is a longitudinal, population-based study of disorders of brain ageing involving the assessment and long-term monitoring of the physical conditions and cognitive status. The target population comprises all Abbiategrasso residents born between 1935 and 1939, a reference sample, according to Population Register data, of around 1,700 people.

Those who agreed to participate in the Invece.Ab study were enrolled in a cross-sectional assessment and will be contacted two and four years after the initial data collection to participate in the longitudinal survey. Both the cross-sectional and longitudinal assessments include a medical evaluation, a neuropsychological test battery, several anthropometric measurements, a social and lifestyle interview, blood analyses, and the storage of a blood sample for the evaluation of putative biological markers.

Last update – 02/05/2017

Country Italy 
Contact details
Institution name Golgi Cenci Foundation 
Principal Investiator (PI) Dr Antonio Guaita 
Contact email Email: [email protected] PI Email:[email protected] 
Contact phone number  
Address Golgi Cenci Foundation
Milan, IT 
Funders (Core support) Federazione Alzheimer Italia 

Variables Collected

Brain related measures: Cognitive function, Mental health, Neurological
Funtional rating: Individual psychological
Anthropometric: Blood pressure, Height, Hip circumference, Waist circumference, Weight
Physical: Cardiovascular, Hearing and Vision, Reproductive, Respiratory
Biological samples: Blood
Genotyping: Gene screening
Brain imaging: N/A
Brain banking: Consent for brain donation
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: Education, Housing and accommodation, Income and finances, Informal support, Marital status, Occupation and employment, Unpaid care
Health service utilisation: N/A
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