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Cohort Acronym

Cohort type
General population-based cohort


Participant type
No diagnosis

Recruitment Period 1991-1993 
Sample size at start or planned sample size if still recruiting 1389  
Estimated Current Sample Size  
Age at Recruitment 59-71   
Gender Male and Female 

The EVA study was a 9-year longitudinal study with 6 waves of follow-ups. During the two-year period 1991-1993 (EVA0), 1389 men and women born between 1922 and 1932 were recruited.

The aim is to investigate vascular ageing, decline in brain and cognitive function and associated factors with a longitudinal follow-up study. The secondary objective is to determine to role of biological factors linked with oxidative stress and brain ageing.
Inclusion criteria Subjects from both genders born between 1922 and 1932 (59 to 71 years old at enrolment), included in electoral registers in Nantes, can speak French and living in Nantes.

Last Update 21/09/2017

Country France 
Contact details
Institution name Institut National de la Sant' et de la Recherche M'dicale 
Principal Investiator (PI) Dr Claudine Berr 
Contact email PI Email: [email protected]  
Contact phone number +33 (0)4 99 61 45 66 
Funders (Core support) MERCK And EISAI 

Variables Collected

Brain related measures: Cognitive function, Mental health, Neurological
Funtional rating: Individual physiological, Individual psychological
Anthropometric: Blood pressure, Height, Weight
Physical: Cardiovascular
Biological samples: Blood
Genotyping: N/A
Brain imaging: N/A
Brain banking: N/A
Lifestyle: Alcohol, Dietary habits, Physical activity, Smoking
Socio-economic: Education, Income and finances, Marital status, Occupation and employment
Health service utilisation: Formal health and social care service utilisation including private care
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