Principal Investigators


C. Franceschi, N. Pedersen, K. Mills, G. Giaccone

Institution


Multiple

Contact information of lead PI


Country


Italy|Sweden|United Kingdom

Title of project or programme


ADAGE: Alzheimer's Disease pathology within the ageing physiology.

Source of funding information


JPND-JPcofuND

Total sum awarded (Euro)


€ 1,130,967

Start date of award


01/01/2016

Total duration of award in years


3.0

The project/programme is most relevant to:


Alzheimer's disease & other dementias

Keywords


Research Abstract


Everybody grows old. But while some people grow old in good health, others experience severe disease, such as Alzheimer’s disease. Recent research demonstrates that Alzheimer’s disease shares several features with the ageing process and suggests that the pathology is the consequence of something that goes wrong during physiological ageing. Researchers involved in ADAGE (Alzheimer’s Disease+AGEing) will use the most advanced biomolecular approaches to compare Alzheimer’s disease patients with people who have stayed healthy in old age, including nonagenarians and centenarians. In this way, resear- chers aim to identify early biomarkers of the disease that will provide new diagnostic, pro- gnostic and therapeutic targets. The ADAGE consortium includes researchers from four insti- tutes in three EU countries (Italy, the UK and Sweden), and will also collaborate with three additional teams in Italy and Switzerland.

Lay Summary


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