Principal Investigators

    Prof Michael Parker


    St Vincent's Institute of Medical Research

    Contact information of lead PI



    Title of project or programme

    Amyloid Precursor Protein Signalosome: directing Abeta production in Alzheimer's disease

    Source of funding information

    National Health and Medical Research Council

    Total sum awarded (Euro)

    € 462,970

    Start date of award


    Total duration of award in years



    Research Abstract

    Alzheimer’s disease is the most common form of dementia and is the fourth biggest killer in developed countries. Amyloid precursor protein plays a central role in the development of the disease, through the generation of a toxic peptide called Abeta. In this project we will decipher the fine molecular details of what the protein looks like and how various molecules known to bind to it affect Abeta production. This knowledge is expected to lead to novel therapies to treat the disease.

    Further information available at:

Types: Investments < €500k
Member States: Australia
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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