Name of Fellow

    Dr Sam Creavin



    Wellcome Trust

    Contact information of fellow


    United Kingdom

    Title of project/programme

    Approaches to diagnosing dementia syndrome in general practice: Determining the value of gestalt judgment, clinical history and tests.

    Source of funding information

    Wellcome Trust

    Total sum awarded (Euro)

    € 435,548

    Start date of award


    Total duration of award in years


    The project/programme is most relevant to:

    Alzheimer's disease & other dementias


    Cognitive impairment | Dementia | Neurodegen

    Research Abstract

    I will investigate whether an evaluation in general practice can have comparable test accuracy to a specialist opinion for diagnosing dementia in symptomatic elderly people. Objective 1: I will systematically review the test accuracy of general practitioners gestalt clinical judgment for the diagnosis of dementia in symptomatic primary care patients and, if indicated, perform a meta-analysis. My hypothesis is that the utility of the gestalt clinical judgment of general practitioners in diagn osing dementia is better than chance but inferior to specialist assessment. Objective 2: I will conduct an empirical, prospective, diagnostic test accuracy (DTA) study comparing GP gut feeling , blood tests, neuroimaging, index collection of cognitive tests suitable for GPs and specialist assessment to a reference consensus expert panel diagnosis. I will identify the most useful components of a diagnostic evaluation in general practice. My hypothesis is that a combination of brief cognitive tests adds diagnostic value to a GP’s gestalt judgment. Objective 3: I will conduct exploratory qualitative research to evaluate the feasibility and acceptability of GP diagnosis of dementia for patients and clinicians, based on the set of tests that I identify as most useful.

Types: Fellowships
Member States: United Kingdom
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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