Principal Investigators


Dr Shyuan Ngo

Institution


University of Queensland

Contact information of lead PI


Country


Australia

Title of project or programme


Bioenergetic deficit in neurodegeneration: studies in motor neuron disease (MND)

Source of funding information


National Health and Medical Research Council

Total sum awarded (Euro)


€ 204,471

Start date of award


01/01/2016

Total duration of award in years


3

Keywords


Research Abstract


Motor neurone disease (MND) is a fatal neurodegenerative disease. There is no known cause and no known cure. We believe that a defect in the way in which the muscle and nerve cells generate energy to sustain survival causes for there to be added metabolic stress on their already high energetic load, ultimately leading to cell death. This project aims to understand the vicious cycle of energy deficiency that leads to the catastrophic events that cause the death of muscle and nerve cells.

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