Name of resource

BRAINS Unit, Lund University

Name of Principal Investigator
First nameDeniz
Last nameKirik
Address of institution where award is held
InstitutionLund University
Street AddressBMC D11
  • Sweden
  • Website

    Contact email

    We run a small vector production facility that makes high quality AAV vectors that we use to develop animal models of PD and HD.

    1a. The resource holds animal models relevant to the study of the following neurodegenerative diseases
  • Parkinson’s disease
  • Huntington’s disease
  • 1b. The resource holds:
  • Animals
  • Frozen embryos
  • Genetic material (DNA, RNA, vectors etc)
  • 2a. The resource acts as a centre for access and distribution to external groups (who are not the PIs of the resource)
    2b. Procedures and rules for access
  • Access through collaboration with PI only
  • 3a. Does the resource develop animal models for external groups


    3b. Types of models provided
    4a This activity is supported as:
  • Independent of collaboration
  • 4b. The supplied material deposited in a central repository


    5a Disease models available
    DiseaseSpeciesAvailable to external user (Y/N)Full phenotypic character (Y/N or partial)PhenotypesGenotypes or other subtypes
    PDrat, mouse, primatepartialpartialDA cell lossalpha-synuclein
    HDrat, mousepartialpartialmetabolic dysfunctionhuntingtin
    5b. Other models/phenotypes available through the resource relevant to neurodegenerative conditions
    No. of modelsAvailable to external usersFull phenotypic characterisation available (Y/N or partial)Nature of phenotype
    1partialpartialbehavior and pathology
    2partialpartialbehavior and pathology
    6. European or international consortia or networks to which the resource is linked
    Jackson Laboratories, USAInternational mouse knockout consortium
    7a. Maintenance of the resource is dependent on continued funding


    7b. End date of current funding period


    7c. Expected lifespan of the resource (in years)


      Types: Experimental Models
      Member States: Sweden
      Diseases: Huntington's disease, Parkinson's disease & PD-related disorders
      Years: 2011
      Database Categories: N/A
      Database Tags: N/A

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