Principal Investigators

    Sipione, Simonetta


    University of Alberta

    Contact information of lead PI



    Title of project or programme

    Cellular lipids in Huntington's disease

    Source of funding information


    Total sum awarded (Euro)

    € 529,970

    Start date of award


    Total duration of award in years


    The project/programme is most relevant to:

    Huntington's disease


    Research Abstract

    Huntington’s disease (HD) is the most common inherited neurodegenerative disorder. It is characterized by progressive motor dysfunction, cognitive decline and psychiatric disturbances. There is currently no cure for this disease. The production of certain lipid molecules that are important for normal functioning of brain cells is impaired in HD. The aim of this proposal is to investigate the consequences of reduced lipid synthesis in HD brain and to test whether restoring normal levels of these important neural molecules improves HD symptoms and slows down disease progression. Supported by encouraging preliminary results, our studies will potentially identify new therapeutic interventions for the cure of HD.

    Lay Summary

    Further information available at:

Types: Investments > €500k
Member States: Canada
Diseases: Huntington's disease
Years: 2016
Database Categories: N/A
Database Tags: N/A

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