Principal Investigators

    McShane, Rupert


    University of Oxford

    Contact information of lead PI


    United Kingdom

    Title of project or programme

    Cochrane Dementia and Cognitive Improvement Group

    Source of funding information


    Total sum awarded (Euro)

    € 890,528

    Start date of award


    Total duration of award in years


    The project/programme is most relevant to:

    Alzheimer's disease & other dementias|Parkinson's disease & PD-related disorders


    Research Abstract

    Prevention, treatment, and management of acute or chronic acquired cognitive impairments, their manifestations and complications, and the care of people affected. Our remit includes both global cognitive impairment and focal cognitive impairments occurring in the context of brain disease such as Alzheimer’s disease, vascular dementia, fronto-temporal dementias including Pick’s disease, dementia with Lewy bodies and the spongiform encephalopathies. It also extends to delirium, and to non-specific and age-associated cognitive impairments. We are concerned, in collaboration with other relevant Cochrane Groups, with cognitive impairment occurring as a complication of diseases such as diabetes, stroke and hypertension. Dementia with Parkinson’s disease and in HIV disease are usually dealt with by the primary disease Groups. Single and complex interventions of all kinds are reviewed, including pharmacological, psychological, environmental, organizational, and alternative or complementary. All relevant outcomes are considered including changes in cognitive function, behaviour, activities of dailyliving, global clinical impression, dependency, carer burden, quality oflife, use of resources, survival and institutionalization. Where suitable data are available, cost-effectiveness comparisons will be included in reviews. Interventions, pharmacological or otherwise, aimed at enhancing cognitive performance in normal people.

    Lay Summary

    Further information available at:

Types: Investments > €500k
Member States: United Kingdom
Diseases: Alzheimer's disease & other dementias, Parkinson's disease & PD-related disorders
Years: 2016
Database Categories: N/A
Database Tags: N/A

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