Name of Resource

    Collection of Gene Edited Cell Lines (Neurobiology Laboratory for Brain Aging & Mental Health, Basal)

    Name of Principal Investigator - Title

    Prof

    Name of Principal Investigator - First name

    Anne

    Name of Principal Investigator - Last name

    Eckert

    Address of institution -Institution

    Psychiatric University Clinics Basel

    Address of institution - Street address

    Wilhelm Klein Str 27

    Address of institution - City

    Basel

    Address of institution - Postcode

    4012

    Country

    Switzerland

    Website
    Contact email
    Summary

    It is a collection setup to support my own research, but can be made available to others via collaborations: cell lines, stably transfected: i) human neuroblastoma cell line SH-SY5Y with empty vector, wtAPP, APPswe (Swedish mutation); ii) HEK293 cells with wtAPP, APPswe; iii) PC12 cells with wtAPP, APPswe

    Q1a. Please indicate below if your cohort includes or expects to include, incidence of the following conditions? (1)

    Alzheimer's disease and other dementias

    Q1b. Does your resource hold

    Gene-edited cell lines (APP,tau)

    Q2a. Does the resource act as a centre for access and distribution to external groups (who are not the Principal Investigators (PI) for the resource)?

    Yes

    Q2b. If Yes, what procedures and rules apply for access?

    Access through collaboration with PI only|Local/ regional access|National access|International access

    Q3a. Does your resource develop experimental models (animal/cell) for external groups?

    No

    Q3b. If YES and your resource is related to an ANIMAL model, what types of models are provided?

    Q3c. If YES and your resource is related to a CELL model, what types of models are provided?

    Gene-edited

    Q4a. Is this activity supported as:

    A collaboration

    Q4b. Do you deposit what you supply in any kind of central repository?

    No

    Disease

    Species

    Available to external user

    Full phenotypic character

    Please indicate the phenotypes

    List of genotypes or other subtypes

    Q5b. Cognitive function, No of models

    Q5b. Cognitive function, Available to external users

    Q5b. Cognitive function, Full phenotypic characterisation

    Q5b. Cognitive function, Nature of phenotype

    Q5b. Motor function, No of models

    Q5b. Motor function, Available to external users

    Q5b. Motor function, Full phenotypic characterisation

    Q5b. Motor function, Nature of phenotype

    Q5b. Physiological function, no of models

    Q5b. Physiological function, Available to external users

    Q5b. Physiological function, Full phenotypic characterisation

    Q5b. Physiological function, Nature of phenotype

    Q5b. Other function (please specify), no of models

    Please specify other function

    Q5b. Other function (please specify), Available to external users

    Q5b. Other function (please specify), Full phenotypic characterisation

    Q5b. Other function (please specify), Nature of phenotype

    Q6. Please indicate if your resource is already linked into European or international consortia or networks?

    Q7a. Is maintenance of this resource dependent on continued funding?

    No

    Q7b. If yes, when does the current funding period end?

    Q7c. What is the expected lifespan of the resource (in years)?

    Currently limited

    Q7d. Are there other plans affecting future use that it may be useful to know?

Types: Experimental Models
Member States: Switzerland
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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