Name of Fellow

    Dr Graciela Muniz Terrera



    Alzheimer's Society

    Contact information of fellow


    United Kingdom

    Title of project/programme

    Evidence synthesis of trajectories of cognitive change due to chronological age, death and preclinical dementia.

    Source of funding information

    Alzheimer's Society

    Total sum awarded (Euro)

    € 178,798

    Start date of award


    Total duration of award in years


    The project/programme is most relevant to:

    Alzheimer's disease & other dementias


    Research Abstract

    Understanding within-person cognitive trajectories is necessary to identify antecedent conditions, potential modifiers, moderating factors and causal processes leading to such trajectories. Education is associated to cognitive decline, but evidence is mixed. Aims are to: (1) synthesise evidence about within-person trajectories of cognitive decline in global and specific cognitive abilities induced by ageing, dementia and proximity to death, (2) synthesise evidence about the effect of education on such trajectories and (3) extend existing methodologies to achieve (1) and (2). Aggregate, individual and a mix of both types of data from published reports, studies members of the IALSA network and from newly identified studies of ageing will be used. Cross study national and international comparisons of trajectories of cognitive decline will be performed. Synthesis about the effect of education on cognitive trajectories of global and specific cognitive abilities due to ageing, proximity to death and preclinical dementia will permit cross national and international comparisons. Standard and alternative formulations of latent growth models will be considered to improve fulfilment of the model’s distributional assumptions. New and strong evidence about within-person trajectories of cognitive decline and about the effect of education on these trajectories will emerge

Types: Fellowships
Member States: United Kingdom
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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