Name of Fellow

    Solomon Alina



    Academy of Finland

    Contact information of fellow



    Title of project/programme

    Fingerprinting the risk of dementia and likelihood of intervention response to facilitate prevention-related decision-making

    Source of funding information

    Academy of Finland

    Total sum awarded (Euro)

    € 434,485

    Start date of award


    Total duration of award in years


    The project/programme is most relevant to:

    Alzheimer's disease & other dementias


    Dementia | Alzheimer disease | prevention | clinical trials | epidemiology | biomarkers | computer-based risk profiling

    Research Abstract

    Dementia and Alzheimer disease prevention is a major public health priority. This project focuses on formulating tools for identifying high-risk individuals who may benefit from preventive interventions. Novel computer-based methods (Disease State Index, Disease State Fingerprint) will be used for analysis and visualization of a broad range of dementia-related factors and biomarkers. Specific aims include: 1) Risk index estimating an individual’s risk of cognitive impairment/dementia; 2) Intervention response index estimating an individual’s likelihood to respond to preventive interventions; 3) Planning a protocol for prevention-related decision-making. The project combines several large observational population-based studies (FINRISK, CAIDE, Vantaa 85+) and prevention trials (FINGER, MAPT, LipiDiDiet). It can produce comprehensive profiling tools that can facilitate personalization of preventive strategies in order to make them more effective.

Types: Fellowships
Member States: Finland
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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