Principal Investigators



    National Institute on Aging

    Contact information of lead PI



    Title of project or programme

    Genetic Analysis Of Alzheimer s Disease

    Source of funding information

    NIH (NIA)

    Total sum awarded (Euro)

    € 608,180.73

    Start date of award

    Total duration of award in years


    The project/programme is most relevant to:

    Alzheimer's disease & other dementias


    Acquired Cognitive Impairment... Aging... Alzheimer's Disease... Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD)... Brain Disorders... Dementia... Genetics... Human Genome... Neurodegenerative... Prevention

    Research Abstract

    We continue to be a contributor to the reanalysis of large tracts of genome wide association data and much of this work, which identifies several new loci, and a converging molecular pathway, has been published. Most recently we continue our efforts using second generation sequencing (which previously lead to the identification of TREM2 and TREML2, and PLD3 variants as a risk factor for Alzheimer’s disease). We have followed up on that work with continued characterization of known AD loci in relatively small series of patients. We are contributing members to consortia that continue to investigate various aspects of AD genetics.

    Lay Summary

    Further information available at:

Types: Investments > €500k
Member States: United States of America
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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