Name of Fellow


Prof Andrew Hill

Institution


Funder


NHMRC

Contact information of fellow


Country


Australia

Title of project/programme


Identifying key steps in the processing of proteins involved in Alzheimer's and prion diseases

Source of funding information


NHMRC

Total sum awarded (Euro)


€ 83,436

Start date of award


01/01/11

Total duration of award in years


6.0

The project/programme is most relevant to:


Alzheimer's disease & other dementias

Keywords


alzheimer disease | prion diseases | neurodegeneration | biochemistry | cell biology

Research Abstract


Alzheimer’s disease is the most common neurodegenerative disease of the ageing population and is associated with toxicity of the Abeta peptide. Prion diseases (eg CJD in humans) are infectious neurodegenerative disorders caused by misfolding of the prion protein. This proposal aims to bring together similar features of these diseases using novel cell and animal based studies to develop better diagnostics and greater understanding of the molecular basis of these disorders with a view to developing interventional therapies.

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