Principal Investigators

    Prof. dr. Johannes de Boer


    VU University of Amsterdam, Dept. of Physics and Astronomy

    Contact information of lead PI



    Title of project or programme

    In vivo optische detectie van Amyloid Beta plaques in de menselijke retina. In vivo optical detection of Amyloid Beta plaques in the human retina

    Source of funding information

    alzheimer nederland (ISAO)

    Total sum awarded (Euro)

    € 100,000

    Start date of award


    Total duration of award in years



    Research Abstract

    At present A? plaque burden is the most important pathological parameter in Alzheimer’s disease (AD) for diagnosis and monitoring of disease progression. We propose to use a novel retinal amyloid imaging technique in order to develop a biomarker for AD that can be easily obtained with minimal patient discomfort. This will enable early diagnosis. In addition, visualization of A? plaques in the retina will be an ideal patient friendly procedure for evaluation of the effects of new therapeutic agents. A new method with minimal cost and patient discomfort will have a huge impact on dementia care, health care costs and quality of life.

    Further information available at:

Types: Investments < €500k
Member States: Netherlands
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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