Principal Investigators


Dr Scott Ayton

Institution


University of Melbourne

Contact information of lead PI


Country


Australia

Title of project or programme


Investigating the cause and consequences of iron deposition in Parkinson's disease

Source of funding information


National Health and Medical Research Council

Total sum awarded (Euro)


€ 312,071

Start date of award


01/01/2016

Total duration of award in years


3

Keywords


Research Abstract


It is known that iron elevation occurs in the brain in Parkinson’s disease. This might cause cell death by ‘rusting’. It is not known (1) how iron accumulates in the disease, (2) whether iron accumulation contributes to the worsening of the disease and (3) if lowering iron with a drug would improve symptoms. We plan to address these questions using a clinical cohort of patients, and laboratory animal models.

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