Principal Investigators

    Enikö Ra?eková

    Institution

    Institute of Neurobiology, of the Slovak Academy of Sciences

    Contact information of lead PI

    Country

    Slovakia

    Title of project or programme

    Investigation of postnatal neurogenesis in relation to neurodegeneration

    Source of funding information

    Ministry of Education, Science, Research and Sport of the Slovak Republic

    Total sum awarded (Euro)

    € 46,500

    Start date of award

    01/01/2015

    Total duration of award in years

    2

    Keywords

    Research Abstract

    The generation and death of newborn cells have critical roles in brain development and maintenance in the adult brain. Specific alterations in these processes are seen in neurodegenerative diseases. The pathogenesis of these diseases is not yet known. It is assumed that the phenomenon of postnatal neurogenesis, respectively its failure may be associated with the development of neurodegenerative diseases. Our previous findings have demonstrated that adverse environmental factors can induce changes in the neurogenesis in the rat olfactory system. The aim of the proposed project is to verify the hypothesis that there is a link between neurogenesis and neurodegeneration. We will investigate if specific alterations in the olfactory system neurogenesis parallel the early symptoms of some neurodegenerative disease, such as depression, anxiety or olfactory dysfunction. The obtained results could contribute to understanding of the role of postnatal neurogenesis in the pathogenesis of neurodegenerative diseases.

    Further information available at:

Types: Investments < €500k
Member States: Slovakia
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

Export as PDF