Name of Fellow

    Dr Gabriela Bodea

    Institution

    Funder

    NHMRC

    Contact information of fellow

    Country

    Australia

    Title of project/programme

    L1 retrotransposition: the missing link between genetics and environmental factors in Parkinson's disease ?

    Source of funding information

    NHMRC

    Total sum awarded (Euro)

    € 403,436

    Start date of award

    01/01/16

    Total duration of award in years

    5.0

    The project/programme is most relevant to:

    Alzheimer's disease & other dementias

    Keywords

    dementia | dopamine | epigenetics | parkinson disease | molecular basis of disease

    Research Abstract

    The study proposed here focuses on understanding the role of specific mobile DNA sequences in the interaction between environmental and genetic risk factors causing Parkinson’s disease (PD) leading to dementia. The project proposes identification of mobile DNA induced mutations in post-mortem human PD patient brain samples. The significance and mechanisms of mobile DNA induced mutations will be then tested in a PD mouse model.

Types: Fellowships
Member States: Australia
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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