Principal Investigators




    Contact information of lead PI



    Title of project or programme

    Life Enhancing Activities for Family Caregivers of People with Dementia

    Source of funding information

    NIH (NIA)

    Total sum awarded (Euro)

    € 2,213,511.01

    Start date of award


    Total duration of award in years


    The project/programme is most relevant to:

    Alzheimer's disease & other dementias


    caregiver interventions, Family Caregiver, informal caregiver, Caregivers, Dementia

    Research Abstract

    DESCRIPTION (provided by applicant): Family members provide the vast majority of informal care to people with dementia and experience significant caregiving-related stress that contributes to mental and physical illness and increases their risk of death. As the number of people diagnosed with dementia is expected to exceed 11 million by 2050, there is a growing need for interventions that can effectively buffer these negative psychological and physical consequences in informal caregivers. The purpose of this randomized clinical trial is to test the Life Enhancing Activities for Family Caregivers (LEAF) intervention, a positive emotion skill-building program designed to improve psychological well-being (positive and negative affect, stress, burden, strain, mood) and coping. The LEAF one-hour training sessions will be conducted weekly for 5 weeks by a trained facilitator. The skills include: noticing and capitalizin on positive events, gratitude, mindfulness, positive reappraisal, personal strengths, and acts of kindness. The intervention is unique in that it is delivered via video conference, as opposed to in-person, which vastly increases the accessibility for caregivers. Also, the nature of the skills taught enable caregivers to use them at any time without needing to schedule an appointment with a provider, travel to a facility, arrange coverage for caregiving in their absence, or incur ay additional financial liability associated with service utilization. Given that sociodemographic factors, specifically age and geographic location, can influence individual caregiver’s experiences, the study will test the effects of the LEAF intervention in a diverse cohort of informal caregivers of individuals with dementia. The specific aims are to: 1) Test the effect of the LEAF intervention compared to the wait list control condition on psychological well-being (positive and negative affect, stress, burden, strain, mood) and coping at end of intervention and 1 month post intervention; 2) Test the effects of caregiver age and geographic location on psychological and coping outcomes; and 3) Assess the longer-term effects of the LEAF intervention on psychological well-being and coping outcomes at 3 and 6 months post intervention. The LEAF intervention has the potential to substantially decrease the public health burden of caregiving. It is innovative in numerous respects in that it focuses on positive emotion, focuses on the caregiver, and has the potential for sustained beneficial effects. It is also easily accessible to geographically dispersed caregivers whose responsibilities and remote location often pose barriers to participation in more traditional caregiving interventions.

    Lay Summary

    PUBLIC HEALTH RELEVANCE: This proposal is submitted in response to the National Institute of Nursing Research RFA-NR-13-001, Addressing Needs of Informal Caregivers of Individuals with Alzheimer’s Disease in the Context of Sociodemographic Factors (R01). It is relevant to the Institute’s mission to promote and improve the health of individuals, families, communities and populations.

    Further information available at:

Types: Investments > €500k
Member States: United States of America
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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