Principal Investigators

    Ka?ovský Petr Prof. MUDr. CSc.


    Faculty Hospital Olomouc

    Contact information of lead PI


    Czech Republic

    Title of project or programme

    Markers of neurodegeneration in differential diagnosis of parkinsonian syndrome

    Source of funding information

    Ministry of Health of the Czech Republic

    Total sum awarded (Euro)

    € 201,000

    Start date of award


    Total duration of award in years



    Research Abstract

    Parkinson syndrome (PS) is characterised by bradykinesis, rest tremor, rigidity and postural instability. The most frequent cause (about 80%) is idiopatic Parkinson’s disease. But also a number of other neurodegenerative diseases , e.g. Lewy body disease, progressive supranuclear palsy, multisystem atrophy, corticobasal degeneration etc., can manifest itself with PS. Differential diagnosis between individual diseases is highly limited. Project goal will be in case of patients with PS and age identical control group to do detailed examination of serum and cerebrospinal fluid with determination of levels of neurodegenerative markers, inflamattory markers, oncomarkers, histic destruction pointers and other. The levels of the markers we took will be from now on compared with the disease process, its possible progression or development in different diseases. Gathered information could be instrumental towards the asessment of possible predictive factor defining disease prediction.

    Further information available at:

Types: Investments < €500k
Member States: Czech Republic
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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