Principal Investigators


A/Pr Brett Collins

Institution


University of Queensland

Contact information of lead PI


Country


Australia

Title of project or programme


Membrane trafficking in Alzheimer's disease

Source of funding information


National Health and Medical Research Council

Total sum awarded (Euro)


€ 320,866

Start date of award


01/01/2013

Total duration of award in years


4

Keywords


Research Abstract


Alzheimer’s disease is a progressive neurological disorder and is the most common cause of dementia. No effective treatments are currently available. The toxic amyloid peptide is central to disease pathology and is derived from breakdown of the Alzheimer’s amyloid precursor protein (APP). In this project we will examine the interactions between APP and the molecular machinery that controls its location in the cell and subsequent degradation.

Further information available at:

Export as PDF