Principal Investigators




    Contact information of lead PI



    Title of project or programme

    Memory Lane: A neuro-exergame to mitigate cognitive decline in later life

    Source of funding information

    NIH (NIA)

    Total sum awarded (Euro)


    Start date of award


    Total duration of award in years



    Acquired Cognitive Impairment... Aging... Alzheimer's Disease... Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD)... Behavioral and Social Science... Brain Disorders... Clinical Research... Clinical Research - Extramural... Dementia... Neurodegenerative... Neurosciences... Physical Activity... Prevention

    Research Abstract

    ? DESCRIPTION (provided by applicant): 1st Playable Productions and Union College propose to develop a commercializable product combining physical exercise and cognitive activities through interactive gaming on a stationary bicycle to help prevent cognitive decline and dementia in older adults. The Interactive Physical and Cognitive Exercise System (iPACES) developed by Union College’s Healthy Aging and Neuropsychology Lab is the first system to combine physical and cognitive interventions, and has already proven to have a greater cognitive benefit to older adults than either of these two interventions alone. While behavioral interventions are unlikely to completely prevent or halt dementia, there is the potential for synergistic physical and cognitive exercise specifically to reduce the risk of onset dementia or slow progression. Creating an affordable and easily distributed product will enable wide access to this intervention, while also furthering understanding of what combinations have biggest impact. This Phase I project includes the development of a game that combines physical and cognitive exercise, a hardware configuration that is safe for older adults and suited for in-home installation, and the further collection of user data to inform further developments in engaging design. Participants will be recruited from area retirement communities and advertising and screened for suitability. Participants are assessed after two weeks of playing the cognitive game, without exercise, then as participants engage in the full experience they are assessed at 2, 6, and 12 weeks. Normative individuals interested in maintaining brain health, patients who are prescribed iPACES to slow or ameliorate cognitive decline, retirement and assisted living communities are all potential beneficiaries of the dementia treatment. The incidence of dementia in North America is projected to nearly triple from 3.4 million cases in 2001 to 9.2 million by 2040, with a worldwide increase from 24 to 81 million over the same time period. Considering multiple causes of dementia, no known cure, and minimal benefit from medication, behavioral interventions to improve brain health are a critical component for extending quality of life for patients, families, and their support systems.

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Types: Investments < €500k
Member States: United States of America
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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