Principal Investigators

    Jean-Marc Gallo


    King's College London

    Contact information of lead PI


    United Kingdom

    Title of project or programme

    Molecular mechanisms of C9ORF72 repeat expansion toxicity in frontotemporal dementia

    Source of funding information

    Alzheimer's Research UK

    Total sum awarded (Euro)

    € 129,313

    Start date of award


    Total duration of award in years



    Research Abstract

    Frontotemporal dementia is the second most prevalent form of early onset dementia after Alzheimer’s disease. A large proportion of frontotemporal dementia cases are caused by a genetic defect that enlarges part of a gene. The aim of this project is to understand how nerve cells from frontotemporal dementia patients handle this defective gene. This knowledge will open the way to the development of treatments to slow down or, hopefully, halt the progression of disease.

    Further information available at:

Types: Investments < €500k
Member States: United Kingdom
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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