Principal Investigators


Agneta Nordberg

Institution


Karolinska Institute

Contact information of lead PI


Country


Sweden

Title of project or programme


Molecular PET imaging of Tau in comparison with AD and non-AD dementia pathology

Source of funding information


The Swedish Brain Foundation

Total sum awarded (Euro)


€ 108,814

Start date of award


01/07/2015

Total duration of award in years


2.5

Keywords


Research Abstract


Differential diagnosis among the different causes of dementia should be as accurate as possible in order to benefit from specific drug /non-drug intervention. AD is the most common
form of neurodegenerative and dementia disorder characterized by initially subtle episodic memory problem followed by gradual loss of cognitive functions and loss of independency. It is characterized by complex neuropathology where dysfunction in brain of processing, deposition
and clearance of beta amyloid (Aß) together with deposition of neurofibrillary tangles as well as inflammatory processes lead to synaptic dysfunction. This application has a focus on
several of these pathological processes for new imaging biomarker development.

Further information available at:

Export as PDF