Name of Fellow

    Dr Prashant Bharadwaj

    Institution

    Funder

    NHMRC

    Contact information of fellow

    Country

    Australia

    Title of project/programme

    Neuroprotective functions of autophagy regulators in Alzheimer's disease

    Source of funding information

    NHMRC

    Total sum awarded (Euro)

    € 289,536

    Start date of award

    01/01/16

    Total duration of award in years

    5.0

    The project/programme is most relevant to:

    Alzheimer's disease & other dementias

    Keywords

    amyloid beta-protein | autophagy | neurodegeneration | amp-activated protein kinase | protein phosphatase

    Research Abstract

    The accumulation of the beta amyloid protein has a central role in AD and enhancing its removal improves memory loss in animal AD models. This project builds on my recent finding of regulators of a cell housekeeping system, “autophagy” which accelerate removal of beta amyloid in cells. This study will advance knowledge into the protective functions of the autophagy regulators in reducing AD symptoms. Findings from this work might provide the basis for developing effective anti-AD therapeutics.

Types: Fellowships
Member States: Australia
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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