Title of project or programme

New biomarkers of motor neuron disease: role in the pathogenesis and possible therapeutic targets

Principal Investigators of project/programme grant
ValentiaBanettoIstituto di Ricerche Farmacologiche Mario NegriItaly
Address of institution of lead PI
InstitutionIstituto di Ricerche Farmacologiche Mario Negri
Street AddressVia La Masa 19
  • Italy
Source of funding information

Telethon Foundation

Total sum awarded (Euro)


Start date of award


Total duration of award in months


The project/programme is most relevant to
  • Motor neurone diseases
Research abstract in English
Lay summary

Evaluation of the capability of potential biomarkers to deliver a right diagnosis of the motor neuron disease (MND) and their use as potential therapeutic targets. Particularly, a biomarker either in patients and in animal models, cyclophillin A, seems to be involved in the process that leads to death of the motor neuron. Further studies on this field could bring to the development of new and effective therapeutic approaches.

    Types: Investments > €500k
    Member States: Italy
    Diseases: Motor neurone diseases
    Years: 2011
    Database Categories: N/A
    Database Tags: N/A

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