Principal Investigators


Prof Ostoja Vucic

Institution


University of Sydney

Contact information of lead PI


Country


Australia

Title of project or programme


Pathophysiology of ALS

Source of funding information


National Health and Medical Research Council

Total sum awarded (Euro)


€ 171,978

Start date of award


01/01/2012

Total duration of award in years


5

Keywords


Research Abstract


Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder, with one Australian dying from ALS every day. The mechanisms underlying the development of ALS remain to be determined. Using a novel neurophysiological technique, it is envisaged that the current proposal will establish that ALS begins in the brain and is mediated by cortical hyperexcitability. Further, a diagnostic test for ALS will be developed ensuring earlier diagnosis and institution of treatment.

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