Principal Investigators

    Prof. Dr. L. van den Berg



    Contact information of lead PI



    Title of project or programme

    Project MinE

    Source of funding information

    Stichting ALS

    Total sum awarded (Euro)

    € 7,300,000

    Start date of award


    Total duration of award in years


    The project/programme is most relevant to:

    Motor neurone diseases


    Research Abstract

    More than 200,000 people worldwide are living with Amyotrophic Lateral Sclerosis (ALS), otherwise known as Motor Neuron Disease (MND) or Lou Gehrig’s disease. Relatively little is known about the cause of this progressively degenerative neurological disease. There is still no treatment. The average life expectancy of ALS patients is three years. It is almost certain that the disease has a genetic basis. Project MinE is a large-scale research initiative devoted to discovering the genetic cause of ALS. The ultimate goal is to identify genes that are associated with ALS. The function of these genes may lead to disease pathways for which treatment can be developed. In this project the full DNA profiles of at least 15,000 people with ALS and 7,500 control subjects will be mapped, and comparative analyses on the resulting data will be performed.

    Lay Summary

    Further information available at:

Types: Investments > €500k
Member States: Netherlands
Diseases: Motor neurone diseases
Years: 2016
Database Categories: N/A
Database Tags: N/A

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