Name of Fellow

    Dr Kathryn Munro

    Institution

    Funder

    NHMRC

    Contact information of fellow

    Country

    Australia

    Title of project/programme

    Protecting synaptic connectivity in Alzheimer's disease

    Source of funding information

    NHMRC

    Total sum awarded (Euro)

    € 389,111

    Start date of award

    01/01/16

    Total duration of award in years

    4.0

    The project/programme is most relevant to:

    Alzheimer's disease & other dementias

    Keywords

    neuroscience | synaptic plasticity | synapse formation | memory | alzheimer disease

    Research Abstract

    In Alzheimer’s disease, connections between neurons (synapses) are progressively damaged. The BACE inhibitor class of drugs entering Phase III clinical trials may slow the pace of neurodegeneration in patients with dementia. However, these drugs may simultaneously have negative effects on synapse function, learning and memory. This study will assess the effect of BACE inhibition on synapse properties and cognition and identify the contribution of key proteins affected by this treatment.

Types: Fellowships
Member States: Australia
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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