Principal Investigators

    A/Pr Siew Yeen Chai


    Monash University

    Contact information of lead PI



    Title of project or programme

    Role of IRAP in Alzheimer's Disease

    Source of funding information

    National Health and Medical Research Council

    Total sum awarded (Euro)

    € 497,838

    Start date of award


    Total duration of award in years



    Research Abstract

    Alzheimer’s disease is a progressive brain disease which is results in memory loss and cell death. All currently prescribed drugs treat the memory loss but are unable to stop the deterioration of brain cells. We have developed a class of drugs that reverse memory loss. These drugs target a protein called insulin-regulated aminopeptidase, IRAP. We recently found that these drugs also reduce the disease pathology. This research proposal aims to investigate the role of IRAP in the initiation or progression of Alzheimer’s disease pathology.

    Further information available at:

Types: Investments < €500k
Member States: Australia
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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