Principal Investigators

    Gauchat, Jean-François M


    Université de Montréal

    Contact information of lead PI



    Title of project or programme

    Roles of cardiotrophin-like cytokine partners in the immune response

    Source of funding information


    Total sum awarded (Euro)

    € 469,967

    Start date of award


    Total duration of award in years



    Research Abstract

    The phenotypes of patients deficient for the gene coding for cardiotrophin-like cytokine (CLC) indicate that this protein has multiple roles in the nervous and immune systems, suggesting that it interacts with multiple partners. We identified two of these partners that could have key roles in autoimmune and Alzheimer diseases. We will investigate the immunoregulatory roles of CLC complexed with these molecules and their functions in models of multiple sclerosis and Alzheimer diseases.

    Further information available at:

Types: Investments < €500k
Member States: Canada
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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