Dr Yifat Glikmann-Johnston
Spatial learning and memory in Huntington's disease
Alzheimer's disease & other dementias
huntington's disease | cognitive assessment | memory | neuroimaging | clinical trial
This project will develop a spatial learning and memory test battery sensitive to dementia in Huntingtons disease, relate the task to atrophy in key brain regions, and then apply the test in a clinical trial aimed at developing a regeneration of damaged brain regions in Huntingtons disease. The overarching goal is to develop a cognitive test that is closely aligned to brain pathology in dementia as a tool for more precise, mechanism-based investigations in the dementia clinical trial setting.