Principal Investigators


A/Pr Daniel Hatters

Institution


University of Melbourne

Contact information of lead PI


Country


Australia

Title of project or programme


Surveying the physiological changes to cells in Huntington's disease

Source of funding information


National Health and Medical Research Council

Total sum awarded (Euro)


€ 243,357

Start date of award


01/01/2013

Total duration of award in years


4

Keywords


Research Abstract


Huntington disease results from a mutation that causes the Htt protein to form abnormal toxic clusters in neurons that eventually leads to cell death. This project will develop and apply new technology to identify how the clustering process damages cells and will measure all the gene expression changes that occur during the clustering process. The project offers much potential for revealing new therapeutic targets to this incurable disease.

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