Principal Investigators

    Dr Bradley Turner


    University of Melbourne

    Contact information of lead PI



    Title of project or programme

    Targeting autophagy to improve protein metabolism in ALS

    Source of funding information

    National Health and Medical Research Council

    Total sum awarded (Euro)

    € 398,117

    Start date of award


    Total duration of award in years



    Research Abstract

    One common feature of MND is the accumulation of protein deposits inside nerve cells which leads to their death. We have identified a potent drug which enhances autophagy, a protective process which breaks down protein deposits inside cells. We have shown that this autophagy enhancer efficiently clears protein deposits linked to MND in the Petri dish. We propose to treat MND mice with this autophagy enhancer and predict that it will slow disease signs, preserve lifespan and protect nerve cells.

    Further information available at:

Types: Investments < €500k
Member States: Australia
Diseases: N/A
Years: 2016
Database Categories: N/A
Database Tags: N/A

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