Name of Fellow

    Dr Peng Lei

    Institution

    Funder

    NHMRC

    Contact information of fellow

    Country

    Australia

    Title of project/programme

    Tau and APP interactions in Neurodegeneration

    Source of funding information

    NHMRC

    Total sum awarded (Euro)

    € 130,043

    Start date of award

    01/01/13

    Total duration of award in years

    4.0

    The project/programme is most relevant to:

    Alzheimer's disease & other dementias

    Keywords

    alzheimer disease | microtubule associated protein (map) | parkinson disease | iron transport | amyloid precursor protein

    Research Abstract

    Recently I co-discovered a novel relationship between the Alzheimer’s amyloid precursor protein and tau, both of which play a role in regulating neuronal iron levels. I predict that multiple failures in iron-regulating systems could foster a toxic iron accumulation in brain, leading to the development of neurodegenerative diseases. I hope to gain a better understanding of their mechanism of action and propose that this pathway is a target for therapeutic intervention.

Types: Fellowships
Member States: Australia
Diseases: Alzheimer's disease & other dementias
Years: 2016
Database Categories: N/A
Database Tags: N/A

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