|Title of PI
|Cerebral imagery and neurologic handicap, Inserm 825
Focus 1 : Development of neuroimaging tools for clinical, cognitive brain research and ultimately clinical practice used: Imaging markers of brain macrostructural and microstructural alterations and connectivity and Imaging markers of brain dysfunction and therapeutic efficiency
– Implementation of a multimodal imaging approach based on anatomical MRI, DTI, iron-MRI and connectivity measures in patient and aged controls.
– Development of innovative radiopharmaceuticals probes coupled with sensitive image analysis tools such as independent component analysis and support vector methods for assessing kinetic uptake in patients, as well as to develop clinically-effective MRSI and MR contrast agents.