Principal Investigators


Malin Wiederholm

Institution


STUNS - The Foundation for Collaboration between the Universities in Uppsala, Business and Society

Contact information of lead PI


Country


Sweden

Title of project or programme


Treatment of Parkinson´s disease by recreating the endogenous L-Dopa/Dopamine production in midbrain

Source of funding information


VINNOVA

Total sum awarded (Euro)


€ 217,628

Start date of award


17/03/2014

Total duration of award in years


2

Keywords


Research Abstract


Our technology is based on the discovery and development of a method for harvesting, purification and culturing of non-manipulated, patient-own (autologous) cells that naturally produce high amounts of dopamine precursor. We believe that these cells will be viable after grafting to the brain and that a relatively simple stereotactic surgical procedure might present a highly potent method for inhibiting or curing Parkinson´s disease (PD). In the anticipated project we will ascertain safety, production and release of L-Dopa/Dopamine in vivo in an Parkinsonian model.

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