Title of the cohort
Uppsala Longitudinal Study of Adult Men
Acronym for cohort
ULSAM
Name of Principal Investigator
| Title | Professor |
| First name | Lars |
| Last name | Lannfelt |
Address of institution where award is held
| Institution | Dept of Public Health and Caring Sciences/Geriatrics |
| Street Address | |
| City | Uppsala |
| Postcode | 75185 |
Country
- Sweden
Website
www.pubcare.uu.se/ULSAM
Contact email
Funding source
1. The cohort includes, or expects to include, incidence of the following conditions
- Alzheimer’s disease and other dementias
- Neurodegenerative disease in general
When studies on the above condition(s) are expected to become possible
- Already possible
2a. Stated aim of the cohort
Increased knowledge about the following disorders in an ageing population: cardiovascular and dementia disorders, diabetes, osteoporosis, nutrition and muscle function, and successful ageing
2b. Features distinguishing this cohort from other population cohorts
Over 40 years follow-up
3a. i) Number of publications that involve use of cohort to date
100
3a. ii) Up to three examples of studies to date (PI, Institution, Title of Study)
3b. Publication list/link to where data or publications are accessible (if available)
3c. Information (i.e. research findings) expected to be gained from the population cohort
4a. Study criteria: age range of participants at recruitment
| Age in years from: | 50 years |
| To (‘until death’ if applicable): | 90+/until death |
4b. Study criteria: inclusion criteria
50-year old men living in Uppsala in 1970-1974
4c. Study criteria: exclusion criteria
None
5. Size of the cohort (i.e. number of participants enrolled)
- 1,000 – 5,000 participants
6a. Measures used to characterise participants
Vascular risk factors, specified dementia disorders, nutrition and muscle metabolism, detailed data on glucose and insulin metabolism, osteoporosis measurements, successful ageing
6b. Additional measures for participants with a clinical disorder
6c. Are there defined primary and secondary endpoints (e.g. defined health parameters)
AD and other dementia disorders, death, stroke etc, successful ageing
7. Study design
- Prospective cohort
8. Cases matched by
Age
9a. Does the study include a specialised subset of control participants
- No
9b. If yes, description of specialised subset of control participants
10a. i) Data collection start date
01-01-1970
10a. ii) Data collection end date
10a iii) Data collection for this study is
- Data analysis ongoing
10b. Plans to continue the cohort study beyond the current projected end date
- No
11. Data collected
- Only through the study
- Through links to medical records
- Through links to other records or registers (such as dental records, police records etc). Please specify
- Death register, National Inpatient Register
12. System in place to enable re-contact with patients for future studies
- Yes (participants have given permission to be re-contacted via the PIs to ask if they would participate in further studies)
13a. Format and availability of data stored in a database
Language used:
13b. Format and availability of data held as individual records
Language used:
14a. Are data available to other groups
Yes
14b. Access policy/mechanisms for access if data are available to other groups
15. Data sharing policy specified as a condition of use
- No requirement to make data publicly available
16a. Are tissues/samples/DNA available to other groups
Yes
16b. i) Description of available tissues/samples/DNA
- Living donors: DNA
16b. ii) Form available tissues/samples/DNA are supplied in
16b. iii) Is the access policy/mechanism for obtaining samples the same as that for obtaining data
17. Is information on biological characteristics available to other groups
- No