Swedish National Study on Aging and Care in Kungsholmen

SNAC-K and SNAC-K MRI Study
Swedish National Study on Aging and Care in Kungsholmen

www.snac-k.se
[email protected]
Swedish Government, VR
Swedish Government, VR

Data collection ongoing|Data analysis ongoing

Swedish, English

Sweden

Primary Samples: Stabilised samples (frozen or fixed)| Secondary samples:(derivatives of primary samples)| Secondary samples: plasma| Secondary samples: DNA

Yes, for all the cohort

Data are avalible on request. List of publication: http://www.snac-k.se/publications/original-articles/

multiple, e.g., global cognition, dementia, AD, ADL, etc. social interview, physical functioning, clinical examination, including geriatric, neurological and psychiatric assessment, cognitive assessment.

No

Other health assessment

Yes – funding applied for/funding awarded

Alzheimer’s disease and other dementias|Neurodegenerative disease in general

Data is held as individual records
No
Data held on computer based records
No
Yes
Apply to PI or co-ordinator at resource| Access independent of collaboration with PI| Local/ regional access| National access| International access| Access restricted to peer-reviewed work| Resource has own ethics approval so usually no need for separate external ethics approval
Data made publicly available after a specified time point
Yes

Yes
To increase our understanding of the aging process and to identify preventive strategies that can lead to improved health and care of the elderly. I carry out several studies within SNAC-K: e.g., (1)Vascular risk factors and mechanisms of cognitive decline in aging; (2)Dementia trends over time; (3)Functional disability (might be due to brain degeneration) trend and determinants over time
My research involces 2 distinguishes in this cohort: (1)epidemiological, clinical, and brain imaging data are integrated; (2)long-term follow-up that fits the need of studying health trends.
100
Wang R, Fratiglioni L, …, Qiu C (PI). KI, Mixed brain pathologies mediate association between vascular factors and cognitive decline. Alzheimers Dementai 2016|Liang Y, …, Qiu (PI). KI, Biological age in the assocaition between BP and mortality. Int J Cardiol 2016|Ding M, Santoni G,…, Qiu C, …, Fratiglioni L (PI). KI, Dementia trends in SNAC, 2010-2014 (ongoing) | Shakersain B Prudent diet may attenuate the adverse effects of Western diet on cognitive decline.| Wei-Li Xu HHEX_23 AA Genotype Exacerbates Effect of Diabetes on Dementia and Alzheimer Disease: A Population-Based Longitudinal Study| Wei-Li Xu HHEX_23 AA Genotype Exacerbates Effect of Diabetes on Dementia and Alzheimer Disease: A Population-Based Longitudinal Study

1,000-5,000 participants
CVD, diabetes, multimorbidity, etc. Proxy interview in case of cognitive impairment
Prospective cohort|Longitudinal|Cross sectional survey
linked to inpatient registry and death certificates

No

01/01/2001
Ongoing
Data collection ongoing|Data analysis ongoing
Through links to medical records

Data summarised in database

No
Database on spreadsheet (e.g. excel)
Database on paper
Swedish National Study on Aging and Care in Kungsholmen
Already possible

Population Cohorts
Sweden
Alzheimer’s disease & other dementias|Neurodegenerative disease in general
2016