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Dev

Joined: October 9, 2025
Articles: 6278

Research News (General)

New Biomarkers for Huntington’s Disease Identified

Drug researchers have identified several new biological markers to measure the progression of the inherited neurodegenerative disorder Huntington’s disease (HD). Their findings, published in the Journal of Experimental Medicine, could benefit clinical trials that test new treatments for the disease.…

Dev
January 3, 2017

JPND Publications

17q21.31 duplication causes prominent tau-related dementia with increased MAPT expression

An article titled “17q21.31 duplication causes prominent tau-related dementia with increased MAPT expression” has been published in the journal Molecular Psychiatry. This work was supported in part by JPND through the PERADES project, selected in the 2012 risk factors call.

Dev
January 2, 2017

Research News (General)

Discovery opens door to new Alzheimer’s treatments

Researchers have shed new light on the nerve cell processes that lead to Alzheimer’s disease, overturning previously held ideas of how the disease develops and opening the door to new treatment options that could halt or slow its progression. The…

Dev
January 2, 2017

JPND Publications

Positron emission tomography in ALS: Towards targeting of molecular pathological hallmarks

“Positron emission tomography in amyotrophic lateral sclerosis: Towards targeting of molecular pathological hallmarks” has been published in the European Journal of Nuclear Medicine and Molecular Imaging. This work was supported in part by JPND through the STRENGTH and RiMod-FTD projects.

Dev
December 21, 2016

Research News (General)

Study shows how neurodegenerative diseases spread through the brain

Synapses, the place where brain cells contact one another, play a pivotal role in the transmission of toxic proteins. This allows neurodegenerative diseases such as Alzheimer’s to spread through the brain, according to new research published in Cell Reports. During…

Dev
December 21, 2016

JPND Publications

Neurofilaments in blood and CSF for diagnosis and prediction of onset in Creutzfeldt-Jakob disease

“Neurofilaments in blood and CSF for diagnosis and prediction of onset in Creutzfeldt-Jakob disease” has been published in Scientific Reports. This work was supported in part by JPND through the BiomarkAPD and Sophia projects, selected in the 2011 biomarkers call,…

Dev
December 15, 2016

Research News (General)

Hunt for Huntington’s Disease Cause Yields Clues

Scientists have uncovered new details about how a repeating nucleotide sequence in the gene for a mutant protein may trigger Huntington’s and other neurological diseases. Researchers used computer models to analyze proteins suspected of misfolding and forming plaques in the…

Dev
December 15, 2016

JPND Publications

Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer’s and Parkinson’s diseases

“Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer’s and Parkinson’s diseases” has been published in the Journal of Neurology, Neurosurgery & Psychiatry. This work was supported in part by JPND.

Dev
December 14, 2016

Research News (General)

Dementia on the downslide, especially among people with more education, study finds

In a hopeful sign for the health of the nation’s brains, the percentage of American seniors with dementia is dropping, a new study finds. The downward trend has emerged despite something else the study shows: a rising tide of three…

Dev
December 14, 2016

JPND Publications

Screening for cognitive dysfunction in ALS: validation of the ECAS using age and education adjusted normative data

“Screening for cognitive dysfunction in ALS: validation of the Edinburgh Cognitive and Behavioural ALS Screen (ECAS) using age and education adjusted normative data” has been published in Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. This research was supported in part by…

Dev
December 13, 2016

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