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Dev

Joined: October 9, 2025
Articles: 6278

Research News (General)

Watching in 3D as Neurons in a Living Mouse Brain Communicate

Researchers are developing technology that would make it possible to record brain activity as it plays out across networks. In research published in Nature Methods, they recorded the activity of thousands of neurons layered within three-dimensional sections of brain as…

Dev
December 13, 2016

JPND Publications

Nanomechanical properties of distinct fibrillar polymorphs of the protein α-synuclein

“Nanomechanical properties of distinct fibrillar polymorphs of the protein α-synuclein” has been published in Scientific Reports. This work was supported in part by JPND through the NeuTARGETs project, selected in the 2013 call for research projects for cross-disease analysis of…

Dev
December 12, 2016

Research News (General)

Protective Molecule Sidelined in ALS Models

Researchers have identified a naturally occurring molecule that has the potential for preserving sites of communication between nerves and muscles in amyotrophic lateral sclerosis (ALS) and over the course of aging — as well as a molecule that interferes with…

Dev
December 12, 2016

JPND Publications

Identifying behavioural changes in ALS: Validation of the Beaumont Behavioural Inventory

“Identifying behavioural changes in ALS: Validation of the Beaumont Behavioural Inventory (BBI)” has been published in Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. This work was supported in part by JPND through the ALS-Care project, selected in the 2012 healthcare call.

Dev
December 9, 2016

Research News (General)

Tracking Alzheimer’s Progression by Analyzing Brain Structure Shape

A novel approach to analyzing brain structure that focuses on the shape, rather than the size, of particular features may allow identification of individuals who are in the early, pre-symptomatic stages of Alzheimer’s disease. A team of investigators used advanced…

Dev
December 9, 2016

JPND Publications

Development of an Automated MRI-Based Diagnostic Protocol for ALS Using Disease-Specific Pathognomonic Features

“Development of an Automated MRI-Based Diagnostic Protocol for Amyotrophic Lateral Sclerosis Using Disease-Specific Pathognomonic Features: A Quantitative Disease-State Classification Study” has been published in PLOS ONE. This work was supported in part by JPND through the SOPHIA project, selected for…

Dev
December 8, 2016

Research News (General)

People with Parkinson’s Show Altered Iron Levels in Their Brains

Iron occurs naturally in the human body. However, in people with Parkinson’s disease it distributes in an unusual way over the brain, according to a new study that has been published in the journal Brain. Researchers applied a special type…

Dev
December 8, 2016

JPND Publications

A Comparative Study of SMN Protein and mRNA in Blood and Fibroblasts in Patients with Spinal Muscular Atrophy and Healthy Controls

“A Comparative Study of SMN Protein and mRNA in Blood and Fibroblasts in Patients with Spinal Muscular Atrophy and Healthy Controls” has been published in PLOS ONE. This work was supported in part by JPND through the STRENGTH project, selected…

Dev
December 5, 2016

Research News (General)

Unique Structure of Brain Blood Vessel Amyloid: Latest Clue to Alzheimer’s Development?

Accumulating amounts of amyloid in the brain have been associated with the development of dementia, including Alzheimer’s disease. Now a team of neuroscience and biochemistry researchers have made a novel discovery that illustrates for the first time the difference between…

Dev
December 5, 2016

JPND Publications

Motion and emotion: anxiety–axial connections in Parkinson’s disease

“Motion and emotion: anxiety–axial connections in Parkinson’s disease” has been published in the Journal of Neural Transmission. This work was supported in part by JPND through the APGeM project, selected for support in the 2012 risk factors call.

Dev
December 2, 2016

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