Category survey

Blood RNA biomarkers of Parkinsons disease and progressive supranuclear palsy

Blood RNA biomarkers of Parkinsons disease and progressive supranuclear palsy Investments > €500k United States of America Parkinson’s disease & PD-related disorders 2016

Remote ischemic conditioning for neuroprotection in vascular cognitive impairment

Remote ischemic conditioning for neuroprotection in vascular cognitive impairment Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

Inflammation and delayed cognitive dysfunction after stroke

Inflammation and delayed cognitive dysfunction after stroke Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

TDP-43 acetylation as a pathogenic modification in ALS & related proteinopathies

TDP-43 acetylation as a pathogenic modification in ALS & related proteinopathies Investments > €500k United States of America Alzheimer’s disease & other dementias|Motor neurone diseases 2016

In vivo Amyloid-Beta Imaging in Mouse Brain Using Stochastic Object Models

In vivo Amyloid-Beta Imaging in Mouse Brain Using Stochastic Object Models Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

C9orf72 hexanucleotide repeat expansion caused neurodegeneration in ALS and FTD

C9orf72 hexanucleotide repeat expansion caused neurodegeneration in ALS and FTD Investments > €500k United States of America Alzheimer’s disease & other dementias|Motor neurone diseases 2016

Mechanisms and Consequences of Heterochromatin Loss in Tauopathies

Mechanisms and Consequences of Heterochromatin Loss in Tauopathies Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

Manifold-valued statistical models for longitudinal morphometic analysis in preclinical Alzheimers disease (AD)

Manifold-valued statistical models for longitudinal morphometic analysis in preclinical Alzheimers disease (AD) Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

Exploring the Role of Aging in Cerebral Ischemic Small Vessel Disease Using Notch3 Mutant Mice

Exploring the Role of Aging in Cerebral Ischemic Small Vessel Disease Using Notch3 Mutant Mice Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

Effects of modified erythropoietin on cognition and neuropathology

Effects of modified erythropoietin on cognition and neuropathology Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

Diagnosis of Alzheimers Disease Using Dynamic High-Order Brain Networks

Diagnosis of Alzheimers Disease Using Dynamic High-Order Brain Networks Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

Cholesterol and the Amyloid Precursor Protein

Cholesterol and the Amyloid Precursor Protein Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

Probing the role of membrane and cholesterol on APP-C99 structure and dynamics

Probing the role of membrane and cholesterol on APP-C99 structure and dynamics Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

Homogeneous Heparan Sulfate Glycopeptides: Synthetic and Functional Studies

Homogeneous Heparan Sulfate Glycopeptides: Synthetic and Functional Studies Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

Multimodal modeling framework for fusing structural and functional connectome data

Multimodal modeling framework for fusing structural and functional connectome data Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

Structure determination by vibrational spectroscopy

Structure determination by vibrational spectroscopy Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

Protein structure and function by hydrogen exchange mass spectrometry analysis

Protein structure and function by hydrogen exchange mass spectrometry analysis Investments > €500k United States of America Alzheimer’s disease & other dementias 2016

EPIGENETIC ANALYSIS OF IPSC-DERIVED DOPAMINERGIC NEURONS AND BLOOD CELLS IN PARKINSON DISEASE.

EPIGENETIC ANALYSIS OF IPSC-DERIVED DOPAMINERGIC NEURONS AND BLOOD CELLS IN PARKINSON DISEASE. Investments < €500k Spain 2016

PHARMACOLOGICAL CHAPERONES FOR GENETIC PRION DISEASES

PHARMACOLOGICAL CHAPERONES FOR GENETIC PRION DISEASES Investments < €500k Spain 2016

WEB-BASED TOOLS FOR NEUROIMAGING AND RADIOTHERAPY FUNCTIONAL ANALYSIS & QUANTIFICATION (SUBPROYECTO IQ-BRAIN)

WEB-BASED TOOLS FOR NEUROIMAGING AND RADIOTHERAPY FUNCTIONAL ANALYSIS & QUANTIFICATION (SUBPROYECTO IQ-BRAIN) Investments < €500k Spain 2016

Mito-ND: Mitochondrial Neurodegeneration

Mito-ND: Mitochondrial Neurodegeneration Investments < €500k Germany|United Kingdom 2016

A new brain-dedicated Positron Emission Tomography (PET) system to identify Beta-amyloid biomarker for the early diagnosis of Alzheimer’s disease and other causes of cognitive decline

A new brain-dedicated Positron Emission Tomography (PET) system to identify Beta-amyloid biomarker for the early diagnosis of Alzheimer’s disease and other causes of cognitive decline Investments < €500k European Commission 2016

Neurodegenerative disease biomarkers based on high quality wireless EEG.

Neurodegenerative disease biomarkers based on high quality wireless EEG. Investments < €500k European Commission 2016

Advanced Regional Translation of Excellence into Medical Innovations for Delayed Aging

Advanced Regional Translation of Excellence into Medical Innovations for Delayed Aging Investments < €500k European Commission 2016

DNA rEpair impaired Mice with accElerated Neurodegeneration as Tool to Improve Alzheimer therapeutics

DNA rEpair impaired Mice with accElerated Neurodegeneration as Tool to Improve Alzheimer therapeutics Investments < €500k European Commission 2016

Prognosis and Diagnosis of Protein Misfolding Diseases by Seeded Aggregation in Microspheres

Prognosis and Diagnosis of Protein Misfolding Diseases by Seeded Aggregation in Microspheres Investments < €500k European Commission 2016

Objective delirium detection with an innovative EEG-based spot monitor

Objective delirium detection with an innovative EEG-based spot monitor Investments < €500k European Commission 2016

Alzheimer’s Disease Diagnosis by Spectroscopy. Accurate and Non-Invasive Medical Device for the Diagnosis of Early Stage Alzheimer’s Disease.

Alzheimer’s Disease Diagnosis by Spectroscopy. Accurate and Non-Invasive Medical Device for the Diagnosis of Early Stage Alzheimer’s Disease. Investments < €500k European Commission 2016

Validation of diagnostic and prognostic biomarkers for Parkinson disease

Validation of diagnostic and prognostic biomarkers for Parkinson disease Investments < €500k European Commission 2016

Biomarker assay development to expedite ALS experimental therapeutic advancement

Biomarker assay development to expedite ALS experimental therapeutic advancement Investments < €500k European Commission 2016

Objective delirium detection with an innovative EEG-based spot monitor

Objective delirium detection with an innovative EEG-based spot monitor Investments < €500k European Commission 2016

Validation of diagnostic and prognostic biomarkers for Parkinson disease

Validation of diagnostic and prognostic biomarkers for Parkinson disease Investments < €500k European Commission 2016

MisingLink: Identification and structural characterization of the primordial cytotoxic conformers of the amyloidogenic cascade: Ideal prevention/diagnostic/therapeutic targets in neurodegeneration

MisingLink: Identification and structural characterization of the primordial cytotoxic conformers of the amyloidogenic cascade: Ideal prevention/diagnostic/therapeutic targets in neurodegeneration Investments < €500k|JPND Projects Ireland|JPND|Poland|Spain 2016

Protection of neurons in vitro and in vivo from Synuclein toxicity by molecular tweezers

Protection of neurons in vitro and in vivo from Synuclein toxicity by molecular tweezers Investments < €500k France|Spain|United Kingdom 2016

Synaptic correlates of learning and memory dysfunction analysed by super-resolution STED microscopy in the hippocampus in vivo

Synaptic correlates of learning and memory dysfunction analysed by super-resolution STED microscopy in the hippocampus in vivo Investments < €500k France|Germany 2016

BAFF/APRIL in the central nervous system

BAFF/APRIL in the central nervous system Investments < €500k France|Germany 2016

Therapeutic targeting of impaired lysosomal flux in Alzheimer’s disease

Therapeutic targeting of impaired lysosomal flux in Alzheimer’s disease Investments < €500k Ireland|United Kingdom 2016

Novel control of MT5-MMP on amyloidogenic and inflammatory pathways: validation in human iPSCs from Alzheimer patients and potential therapeutic perspectives

Novel control of MT5-MMP on amyloidogenic and inflammatory pathways: validation in human iPSCs from Alzheimer patients and potential therapeutic perspectives Investments < €500k France|Germany 2016

Identifying effectors of mutant C9Orf72 ALS/FTD to combat neurodegeneration

Identifying effectors of mutant C9Orf72 ALS/FTD to combat neurodegeneration Investments < €500k France|United Kingdom 2016

Using C. elegans to understand seeding and spreading of tau aggregation

Using C. elegans to understand seeding and spreading of tau aggregation Investments < €500k Germany|United Kingdom 2016

Cardiff Fetal Tissue Bank: Quality assured tissue for biomedical research and clinical trial in neurodegenerative disease

Cardiff Fetal Tissue Bank: Quality assured tissue for biomedical research and clinical trial in neurodegenerative disease Investments < €500k United Kingdom 2016

Repurposing Low-Cost Consumer Technology for Motion Correction in Dementia Neuroimaging

Repurposing Low-Cost Consumer Technology for Motion Correction in Dementia Neuroimaging Investments < €500k United Kingdom 2016

Developing a methodological framework for trials in presymptomatic neurodegenerative disease – the Presymptomatic Neurodegeneration Initiative (PreNI)

Developing a methodological framework for trials in presymptomatic neurodegenerative disease – the Presymptomatic Neurodegeneration Initiative (PreNI) Investments < €500k United Kingdom 2016